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RabbitAnti-CR1L Rabbit pAb  antibody (bs-14042R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-14042R
英文名称 CR1L Rabbit pAb
中文名称 补体受体1样蛋白抗体
别    名 Cr1; Crry; CR1L_RAT; Cr1l; Antigen 5I2; Complement regulatory protein Crry; CR1L_MOUSE; Protein p65; Cry;   
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,  (predicted: Human, Rat, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 64 kDa
检测分子量 64
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CR1L: 61-160/569 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 CR16 is a 483 amino acid proline-rich cytoplasmic protein that is thought to regulate cytoskeletal organization. A member of both the verprolin and Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) families, CR16 colocalizes with N-WASP (Neuronal Wiskott-Aldrich syndrome protein) in tips of growth cone filopodia, primary hippocampal neurons and Sertoli cell-spermatid junctions. CR16 and N-WASP functionally interact to influence spermatogenesis. CR16 is predominantly expressed in brain and testis, contains one WH2 domain, a KLKR motif, three profilin-binding motifs and is encoded by a gene that maps to human chromosome 7p15.1.

Function:
Interacts with iC4 (methylamine-treated C4) but not for iC3 (methylamine-treated C3). Belongs to the receptors of complement activation (RCA) family. Contains 8 Sushi (CCP/SCR) domains.

Subcellular Location:
Cytoplasm. Membrane. Secreted. Note: Predominantly found in association with the membrane fraction, but also located in the cytoplasm and in the supernatant.

Gene ID:
54243

Database links:

Entrez Gene: 1379 Human

Omim: 605886 Human

SwissProt: Q2VPA4 Human



产品图片
Sample: Lymph node (Mouse) Lysate at 40 ug Thymus (Mouse) Lysate at 40 ug Lung (Mouse) Lysate at 40 ug Primary: Anti- CR1L (bs14042R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 64kD Observed band size: 64kD
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