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RabbitAnti-CYP2C18 Rabbit pAb  antibody (bs-14150R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-14150R
英文名称 CYP2C18 Rabbit pAb
中文名称 细胞色素P450 2C18抗体
别    名 (S) mephenytoin hydroxylase associated cytochrome P450; CPCI; CYP2C 18; CYP2C; CYP2C17; CP2CI_HUMAN; CYPIIC18; Cytochrome P450 2C18; Cytochrome P450 6B/29C; Cytochrome P450 family 2 subfamily C polypeptide 18; Cytochrome P450 subfamily IIC(mephenytoin 4 h  
研究领域 细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Pig, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 56 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYP2C18: 401-490/490 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C18 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

SWISS:
P33260

Gene ID:
1562

Database links:

Entrez Gene: 1562 Human

Omim: 601131 Human

SwissProt: P33260 Human



产品图片
Sample: Liver (Mouse) Lysate at 40 ug Cerebellum (Mouse) Lysate at 40 ug HL60(Human) Cell Lysate at 30 ug Primary: Anti- CYP2C18 (bs-14150R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD
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