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RabbitAnti-ELK3 Rabbit pAb  antibody (bs-14565R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-14565R
英文名称 ELK3 Rabbit pAb
中文名称 血清反应因子辅助蛋白SAP2抗体
别    名 ELK3; ELK3, ETS domain protein(SRF accessory protein 2); ELK3_HUMAN; ERP; ETS domain protein; ETS domain-containing protein Elk-3; ETS related protein ERP; ETS related protein NET; ETS-related protein ERP; ETS-related protein NET; NET; SAP 2; SAP-2; SAP2; Serum response factor accessory protein 2; SRF accessory protein 2.  
研究领域 细胞生物  免疫学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 44 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELK3: 41-140/407 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. [provided by RefSeq, Jul 2008]

Function:
May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.

Subunit:
Interacts with CTBP1.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.

SWISS:
P41970

Gene ID:
2004

Database links:

Entrez Gene: 2004 Human

Entrez Gene: 417919 Chicken

Entrez Gene: 541125 Cow

Entrez Gene: 482613 Dog

Entrez Gene: 13713 Mouse

Entrez Gene: 362871 Rat

Omim: 600247 Human

SwissProt: P41970 Human

SwissProt: P41971 Mouse

Unigene: 46523 Human

Unigene: 4454 Mouse

Unigene: 196088 Rat



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