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RabbitAnti-GALNTL6 Rabbit pAb  antibody (bs-16229R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-16229R
英文名称 GALNTL6 Rabbit pAb
中文名称 GALNTL6蛋白抗体
别    名 GALNACT20; GALNT17; GalNAc-T6L; 1700021K10Rik; 4930431L04Rik; A830023L05; RGD1564773; GLTL6_HUMAN; GALNTL6; Polypeptide GalNAc transferase 17 (GalNAc-T17 | pp-GaNTase 17); Protein-UDP acetylgalactosaminyltransferase 17; Putative polypeptide N-acetylgalact  
研究领域 细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 70 kDa
检测分子量 70
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GALNTL6: 451-550/601 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 GalNAc-T17 is a 601 amino acid single-pass type II membrane protein that is a member of the glycosyltransferase 2 family and GalNAc-T subfamily. Localized to the Golgi apparatus and contains a ricin B-type lectin domain, GalNAc-T17 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GalNAc-T17 contains two conserved domains, an N-terminal domain (domain A, also called GT1 motif), which is likely involved in manganese coordination and substrate binding and a C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-T17 exists as two alternatively spliced isoforms and utilizes manganese and calcium as cofactors.

Function:
GalNAc-T17 is a 601 amino acid single-pass type II membrane protein that is a member of the glycosyltransferase 2 family and GalNAc-T subfamily. Localized to the Golgi apparatus and contains a ricin B-type lectin domain, GalNAc-T17 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GalNAc-T17 contains two conserved domains, an N-terminal domain (domain A, also called GT1 motif), which is likely involved in manganese coordination and substrate binding and a C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-T17 exists as two alternatively spliced isoforms and utilizes manganese and calcium as cofactors

Subcellular Location:
Golgi apparatus membrane.

Similarity:
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Contains 1 ricin B-type lectin domain.

SWISS:
Q49A17

Gene ID:
442117

Database links:

Entrez Gene: 442117 Human

Entrez Gene: 615819 Cow

Entrez Gene: 486063 Dog

Entrez Gene: 270049 Mouse

Entrez Gene: 361142 Rat

Omim: 615138 Human

SwissProt: Q49A17 Human

Unigene: 386236 Human

Unigene: 236368 Mouse

Unigene: 214629 Rat



产品图片
Sample: Testis(Rat) Lysate at 40 ug Primary: Anti-GALNTL6 (bs-16229R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70 kD Observed band size: 70 kD
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