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RabbitAnti-KIAA1881 Rabbit pAb  antibody (bs-17031R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-17031R
英文名称 KIAA1881 Rabbit pAb
中文名称 KIAA1881蛋白抗体
别    名 KIAA1881; MDRV; MRUPAV; NIPA2; S3-12; PLIN4_HUMAN; PLIN4; Adipocyte protein S3-12;   
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human, Mouse, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 134 kDa
检测分子量 134
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIAA1881: 401-500/1357 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 S3-12 (Adipocyte protein S3-12), also known as PLIN4 (Perilipin-4), is a 1,357 amino acid protein that belongs to the perilipin family. S3-12 contains a repeated 33–amino acid motif also found in adipophilin, and it shares protein sequence identity to both adipophilin and TIP-47 in the COOH terminus, but not to perilipin. S3-12 exhibits sequence similarity to the PAT proteins. Up-regulated during adipocyte differentiation, S3-12 may play a role in triacylglycerol packaging into adipocytes, and functions as a coat protein involved in the biogenesis of lipid storage droplets. S3-12 demonstrates highest expression in skeletal muscle, followed by heart and liver, and lowest expression in adult whole brain. Existing as two alternatively spliced isoforms, the S3-12 gene is conserved in dog, cow and mouse, and maps to human chromosome 19p13.3.

Function:
May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets.

Subcellular Location:
Cell membrane. Cytoplasm. Lipid droplet. Nascent lipid droplet surface-associated; association with lipid droplets is triacylglycerol synthesis-dependent.

Similarity:
Belongs to the perilipin family.

SWISS:
Q96Q06

Gene ID:
729359

Database links:

Entrez Gene: 729359 Human

Omim: 613247 Human

SwissProt: Q96Q06 Human

Unigene: 591387 Human



产品图片
Sample: Ovary (Mouse) Lysate at 40 ug Primary: Anti-KIAA1881 (bs-17031R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 134 kD Observed band size: 134 kD
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