产品编号 | bs-18284R |
英文名称 | LINGO2 Rabbit pAb |
中文名称 | 富含亮氨酸重复跨膜神经元2抗体 |
别 名 | LERN3; Leucine rich repeat and Ig domain containing 2; Leucine rich repeat neuronal 6C; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal protein 6C; LIGO2_HUMAN; LINGO2; LRRN6C. |
研究领域 | 细胞生物 神经生物学 跨膜蛋白 细胞膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Zebrafish, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 65 kDa |
检测分子量 | |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LINGO2: 331-430/606 <Extracellular> |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Lingo-2 (leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2), also known as LERN3 (leucine-rich repeat neuronal protein 3) or LRRN6C, is a 606 amino acid single-pass type I membrane protein. Lingo-2 contains 1 immunoglobulin-like C2-type domain and 13 leucine-rich repeats. Lingo-2 is a member of the LRR gene family and has been linked to essential tremor and Parkinson’s disease. Lingo-2 has a high degree of homology (61%) with Lingo-1, a regulator of neuronal death, and the expression of Lingo-2 seems to be restricted to neuronal tissue. Subcellular Location: Membrane. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 12 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. SWISS: Q7L985 Gene ID: 158038 Database links: Entrez Gene: 158038 Human Entrez Gene: 242384 Mouse Omim: 609793 Human SwissProt: Q7L985 Human SwissProt: Q3URE9 Mouse Unigene: 726303 Human Unigene: 745029 Human Unigene: 132507 Mouse |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |