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RabbitAnti-MAN2A2 Rabbit pAb  antibody (bs-18646R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-18646R
英文名称 MAN2A2 Rabbit pAb
中文名称 α-甘露糖苷酶2x抗体
别    名 3-1; 6-alpha-mannosidase; alpha-mannosidase 2x; alpha-mannosidase IIx; MA2A2_HUMAN; MAN IIx; MAN2A2; MANA2X; Mannosidase alpha class 2A member 2; Mannosyl-oligosaccharide 1; Mannosyl-oligosaccharide 1, 3-1, 6-alpha-mannosidase; MX.  
研究领域 细胞生物  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 131 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAN2A2: 1-100/1150 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 MAN2A2 is a single-pass type II membrane protein that localizes to the cisternae of the golgi and is involved in protein modification pathways. More specifically, MAN2A1 uses zinc as a cofactor to catalyze the first committed step in the formation of N-glycans, namely the hydrolysis of the terminal alpha-D-mannose residues in the oligosaccharide Man5(GlcNAc)3.

Function:
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.

Subcellular Location:
Golgi apparatus membrane.

Similarity:
Belongs to the glycosyl hydrolase 38 family.

SWISS:
P49641

Gene ID:
4122

Database links:

Entrez Gene: 4122 Human

Entrez Gene: 140481 Mouse

Omim: 600988 Human

SwissProt: P49641 Human

SwissProt: Q8BRK9 Mouse

Unigene: 116459 Human

Unigene: 269245 Mouse



产品图片
Sample: LOVO(Human) Cell Lysate at 30 ug FHC(Human) Cell Lysate at 30 ug Primary: Anti-MAN2A2 (bs-18646R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 131 kD Observed band size: 131 kD
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