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RabbitAnti-MINPP1 Rabbit pAb antibody (bs-18942R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-18942R
英文名称 MINPP1 Rabbit pAb
中文名称 多聚磷酸肌醇磷酸酶1抗体
别    名 HIPER1; MINPP2; MIPP; PCH16; MINP1_HUMAN; MINPP1; 2,3-bisphosphoglycerate 3-phosphatase (2,3-BPG phosphatase); 3.1.3.62; MINP1_MOUSE; MINP1_RAT; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase (Ins(1,3,4,5)P(4) 3-phosphatase); multiple inositol-polyphosphate phosphatase 1; multiple inositol polyphosphate histidine phosphatase, 1  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 52kDa
检测分子量 52
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MINPP1: 1-100/487 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009]

Function:
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) (By similarity). May play a role in bone development (endochondral ossification).

Subcellular Location:
Endoplasmic reticulum lumen.

Tissue Specificity:
Widely expressed with highest levels in kidney, liver and placenta.

DISEASE:
Note=Defects in MINPP1 may be involved in follicular thyroid tumors development.

SWISS:
Q9UNW1

Gene ID:
9562

Database links:

Entrez Gene: 9562 Human

Entrez Gene: 17330 Mouse

Entrez Gene: 29688 Rat

Omim: 605391 Human

SwissProt: Q9UNW1 Human

SwissProt: Q9Z2L6 Mouse

SwissProt: O35217 Rat

Unigene: 121260 Human

Unigene: 255116 Mouse

Unigene: 398664 Mouse

Unigene: 27882 Rat



产品图片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-MINPP1 (bs-18942R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
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