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RabbitAnti-NAPRT1 Rabbit pAb  antibody (bs-19017R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-19017R
英文名称 NAPRT1 Rabbit pAb
中文名称 烟酸磷酸NAPRT1抗体
别    名 FHA HIT interacting protein; FHA-HIT-interacting protein; FHIP; FHIP; NAPRT1; NAPRTase; Nicotinate phosphoribosyltransferase; Nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; Nicot  
研究领域 肿瘤  细胞生物  信号转导  激酶和磷酸酶  新陈代谢  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAPRT1: 351-450/538 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008]

Function:
Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells.

Tissue Specificity:
Cytoplasm > cytosol.

Similarity:
Belongs to the NAPRTase family.

SWISS:
Q6XQN6

Gene ID:
93100

Database links:

Entrez Gene: 399559 Cow

Entrez Gene: 93100 Human

Entrez Gene: 223646 Mouse

Entrez Gene: 315085 Rat

Entrez Gene: 393864 Zebrafish

Omim: 611552 Human

SwissProt: A5PK51 Cow

SwissProt: Q6XQN6 Human

SwissProt: Q8CC86 Mouse

SwissProt: Q6XQN1 Rat

SwissProt: Q6P3H4 Zebrafish

Unigene: 493164 Human

Unigene: 288368 Mouse

Unigene: 22665 Rat

Unigene: 29094 Zebrafish



产品图片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-NAPRT1 (bs-19017R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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