产品编号 | bs-19017R |
英文名称 | NAPRT1 Rabbit pAb |
中文名称 | 烟酸磷酸NAPRT1抗体 |
别 名 | FHA HIT interacting protein; FHA-HIT-interacting protein; FHIP; FHIP; NAPRT1; NAPRTase; Nicotinate phosphoribosyltransferase; Nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; Nicot |
研究领域 | 肿瘤 细胞生物 信号转导 激酶和磷酸酶 新陈代谢 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 58 kDa |
检测分子量 | |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NAPRT1: 351-450/538 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008] Function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. Tissue Specificity: Cytoplasm > cytosol. Similarity: Belongs to the NAPRTase family. SWISS: Q6XQN6 Gene ID: 93100 Database links: Entrez Gene: 93100 Human Entrez Gene: 223646 Mouse Entrez Gene: 393864 Zebrafish Omim: 611552 Human SwissProt: Q6XQN6 Human SwissProt: Q8CC86 Mouse SwissProt: Q6P3H4 Zebrafish Unigene: 493164 Human Unigene: 288368 Mouse Unigene: 22665 Rat Unigene: 29094 Zebrafish |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |