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RabbitAnti-MYO1E Rabbit pAb  antibody (bs-19169R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-19169R
英文名称 MYO1E Rabbit pAb
中文名称 肌球蛋白1E抗体
别    名 FSGS6; HuncM-IC; MYO1C; 2310020N23Rik; 9130023P14Rik; myosin-1e; myr 3; MYR5; Myr3; MYO1E_HUMAN; MYO1E; Myosin-Ic; Unconventional myosin 1E; MYO1E_RAT; Myosin heavy chain myr 3;   
研究领域 细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat, )
产品应用 WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 127 kDa
检测分子量 127
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MYO1E: 501-600/1108 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17. [provided by RefSeq, Jan 2012]

Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.

Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.
Contains 1 SH3 domain.

SWISS:
Q12965

Gene ID:
4643

Database links:

Entrez Gene: 4643 Human

Entrez Gene: 71602 Mouse

Entrez Gene: 25484 Rat

Omim: 601479 Human

SwissProt: Q12965 Human

SwissProt: Q63356 Mouse

SwissProt: Q63356 Rat

Unigene: 654506 Human

Unigene: 249311 Mouse

Unigene: 8737 Rat



产品图片
Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-MYO1E (bs-19169R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 127 kD Observed band size: 127 kD
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