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RabbitAnti-NLRC5 Rabbit pAb  antibody (bs-19284R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-19284R
英文名称 NLRC5 Rabbit pAb
中文名称 NLRC5蛋白抗体
别    名 CLR16.1; NOD27; NOD4; NLRC5_HUMAN; NLRC5; Caterpiller protein 16.1 (CLR16.1); Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4; NLRC5_MOUSE;   
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human, 
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 204 kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NLRC5: 651-750/1866 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]

Function:
Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.

Similarity:
Belongs to the NLRP family.
Contains 26 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.

SWISS:
Q86WI3

Gene ID:
84166

Database links:

Entrez Gene: 84166 Human

Entrez Gene: 434341 Mouse

Omim: 613537 Human

SwissProt: Q86WI3 Human

SwissProt: C3VPR6 Mouse

Unigene: 528836 Human

Unigene: 334720 Mouse



产品图片
Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NLRC5) Polyclonal Antibody, Unconjugated (bs-19284R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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