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RabbitAnti-SLC6A14 Rabbit pAb  antibody (bs-21023R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-21023R
英文名称 SLC6A14 Rabbit pAb
中文名称 碳酸氢钠协同转运蛋白6-A14抗体
别    名 BMIQ11; 1110007A17Rik; 9030613J17Rik; ATB0plus; CATB0plus; Atb0+; S6A14_HUMAN; SLC6A14; Amino acid transporter ATB0+; Solute carrier family 6 member 14; S6A14_MOUSE; Colonic system B0+ amino acid transporter CATB0+;   
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 72 kDa
检测分子量 107
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC6A14: 161-260/642 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010]

Function:
Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na+/Cl--dependent manner.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis.

DISEASE:
Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by significant differences in allele frequencies between obese and non-obese individuals.

Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily.

SWISS:
Q9UN76

Gene ID:
11254

Database links:

Entrez Gene: 11254 Human

Entrez Gene: 56774 Mouse

Entrez Gene: 298340 Rat

Omim: 300444 Human

SwissProt: Q9UN76 Human

SwissProt: Q9JMA9 Mouse



产品图片
Sample: HL-60(Human) Cell Lysate at 30 ug Primary: Anti-SLC6A14 (bs-21023R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 72 kD Observed band size: 107 kD
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