| 产品编号 | bs-9590R |
| 英文名称 | PDE4B Rabbit pAb |
| 中文名称 | 磷酸二酯酶4B抗体 |
| 别 名 | DPDE4; PDEIVB; dunce; PDE4/IVb; Pde4B1; Pde4B2; Pde4B3; Pde4B4; Pde4b5; Pde4b_v1; Pde4b_v2; Pde4b_v3; Pde4b_v4; PDE4B_HUMAN; PDE4B; PDE32; cAMP-specific phosphodiesterase 4B; 3.1.4.53; PDE4B_RAT; phosphodiesterase 4B; phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4); phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); phosphodiesterase 4B, cAMP-specific; phosphodiesterase E4 dunce homolog (Drosophila); cAMP-specific 3',5'-cyclic phosphodiesterase 4B |
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Specific References (1) | bs-9590R has been referenced in 1 publications.
111
[IF=8.739] Hailou Zhang. et al. Synergistic effects of two natural compounds of iridoids on rapid antidepressant action by up-regulating hippocampal PACAP signaling. 2022 Mar 31 WB ; Mouse. 222
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| 研究领域 | 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 107kDa |
| 检测分子量 | 107 |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PDE4B: 1-100/736 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] Function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. Tissue Specificity: Expressed in brain, heart, lung and skeletal muscle. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. SWISS: Q07343 Gene ID: 5142 Database links: Entrez Gene: 5142 Human Entrez Gene: 18578 Mouse Omim: 600127 Human SwissProt: Q07343 Human Unigene: 198072 Human Unigene: 20181 Mouse Unigene: 37733 Rat |
| 产品图片 |
Sample:MCF-7 (Human) cellLysate at 40 ug
Primary: Anti-PDE4B(bs-9590R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 107kD
Observed band size: 107kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
