| 产品编号 | bs-12660R |
| 英文名称 | SNRPB Rabbit pAb |
| 中文名称 | 小核糖核蛋白SNRPB抗体 |
| 别 名 | B polypeptide of Sm protein; COD; RSMB_HUMAN; Sm B/B'; Sm B/Sm B'; Sm B/SmB'; Sm protein B/B''; Sm-B/B''; Small nuclear ribonucleoprotein polypeptide B; Small nuclear ribonucleoprotein polypeptide B/B'; Small nuclear ribonucleoprotein polypeptides B and B'; Small nuclear ribonucleoprotein polypeptides B and B1; Small nuclear ribonucleoprotein-associated proteins B and B''; SmB; SmB/B''; SmB/Sm B'; SmB/SmB'; snRNP B; snRNP-B; snRNPB; SNRPB; SNRPB1. |
| 研究领域 | 细胞生物 免疫学 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 24 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SNRPB: 1-100/240 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008] Function: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. Subcellular Location: Nucleus. Post-translational modifications: Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine. Similarity: Belongs to the snRNP SmB/SmN family. SWISS: P14678 Gene ID: 6628 Database links: Entrez Gene: 6628 Human Entrez Gene: 20638 Mouse Omim: 182282 Human SwissProt: P14678 Human SwissProt: P27048 Mouse Unigene: 83753 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
