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RabbitAnti-PNPLA3 Rabbit pAb  antibody (bs-12745R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-12745R
英文名称 PNPLA3 Rabbit pAb
中文名称 脂肪营养素PNPLA3抗体
别    名 Acylglycerol O acyltransferase; Adiponutrin; ADPN; C22orf20; Calcium independent phospholipase A2 epsilon; DJ796I17.1; iPLA(2)epsilon; IPLA2-epsilon; Patatin like phospholipase domain containing 3; patatin like phospholipase domain containing protein 3; phospholipase A2, calcium independent, epsilon.  
研究领域 肿瘤  心血管  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human, 
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 53 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PNPLA3: 101-200/481 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008]

Function:
Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities.

Subcellular Location:
Membrane; Single pass type II membrane protein.

DISEASE:
Disease susceptibility is associated with variations affecting the gene represented in this entry.
Disease description:A condition characterized by accumulation of triglycerides in the liver. It is associated with adverse metabolic consequences, including insulin resistance and dyslipidemia. In a subset of individuals, hepatic steatosis promotes an inflammatory response in the liver, referred to as steatohepatitis, which can progress to cirrhosis and liver cancer. NAFLD is the most common form of liver disease in Western countries.

Similarity:
Contains 1 patatin domain.

SWISS:
Q9NST1

Gene ID:
80339

Database links:

Entrez Gene: 609368 Dog

Entrez Gene: 101131854 Gorilla

Entrez Gene: 101824852 Hamster

Entrez Gene: 80339 Human

Entrez Gene: 100406659 Marmoset (common)

Entrez Gene: 116939 Mouse

Entrez Gene: 100344884 Rabbit

Entrez Gene: 362972 Rat

Omim: 609567 Human

SwissProt: Q9NST1 Human

SwissProt: Q91WW7 Mouse

Unigene: 654800 Human

Unigene: 390817 Mouse

Unigene: 97779 Rat



产品图片
Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-PNPLA3 (bs-12745R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53/58 kD
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