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RabbitAnti-VRK2 Rabbit pAb  antibody (bs-12780R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-12780R
英文名称 VRK2 Rabbit pAb
中文名称 丝氨酸/苏氨酸蛋白激酶vrk2抗体
别    名 2810003O05Rik; AI447698; EC 2.7.11.1; Serine/threonine protein kinase VRK2; Serine/threonine-protein kinase VRK2; Vaccinia related kinase 2; Vaccinia virus B1R related kinase 2; Vaccinia-related kinase 2; VRK 2; VRK2; VRK2_HUMAN.  
研究领域 肿瘤  细胞生物  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Chicken, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VRK2: 151-250/508 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]

Function:
Probable serine/threonine kinase.

Subcellular Location:
Membrane.

Tissue Specificity:
Widely expressed. Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis.

Similarity:
Belongs to the protein kinase superfamily.
CK1 Ser/Thr protein kinase family.
VRK subfamily.
Contains 1 protein kinase domain.

SWISS:
Q86Y07

Gene ID:
7444

Database links:

Entrez Gene: 7444 Human

Entrez Gene: 69922 Mouse

Omim: 602169 Human

SwissProt: Q86Y07 Human

SwissProt: Q8BN21 Mouse

Unigene: 728198 Human

Unigene: 285351 Mouse



产品图片
Sample: Embryo (Mouse) Lysate at 40 ug Liver (Mouse) Lysate at 40 ug Primary: Anti-VRK2 (bs-12780R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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