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RabbitAnti-FPR1 Rabbit pAb  antibody (bs-23519R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-23519R
英文名称 FPR1 Rabbit pAb
中文名称 甲酸基肽受体1抗体
别    名 FMLP; FPR; FPR1_HUMAN; FPR1; fMLP receptor; N-formyl peptide receptor (FPR); N-formylpeptide chemoattractant receptor;   
研究领域 信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse, 
产品应用 WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 40 kDa
检测分子量 55
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse FPR1: 131-230/364 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]

Function:
High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Cell membrane; Multi-pass membrane protein.

Database links:
UniProtKB - P33766 

转录调节因子(Transcriptin Regulators) FPR1属于G蛋白偶联受体家族成员,参与细胞信号传导,激活MAPK通路,免疫应答。
产品图片
Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti-FPR1 (bs-23519R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 55 kD
Sample: BV-2(Mouse) Cell Lysate at 30 ug Primary: Anti-FPR1 (bs-23519R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 55 kD
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