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RabbitAnti-IL10RB Rabbit pAb  antibody (bs-21981R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-21981R
英文名称 IL10RB Rabbit pAb
中文名称 白细胞介素-10受体β抗体
别    名 CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IBD25; IL-10R2; IL-10RB; 6620401D04Rik; D16H21S58; D21S58h; Il10r2; RGD1560373; I10R2_HUMAN; IL10RB; IL-10 receptor subunit beta; IL-10R subunit beta; Cytokine receptor class-II member 4; Cytokine receptor family 2   
研究领域 免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human, 
产品应用 WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 39 kDa
检测分子量 33
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL10RB : 151-250/325 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Interleukin 10 binds specifically and with high affinity to cell surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. Mouse and human cDNA clones encoding the ligand binding IL10 receptor have been isolated. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10.

Subcellular Location:
Membrane; Single-pass type I membrane

Similarity:
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains.

SWISS:
Q08334

Gene ID:
3588

Database links:

Entrez Gene: 3588 Human

Entrez Gene: 16155 Mouse

Entrez Gene: 304091 Rat

Omim: 123889 Human

SwissProt: Q08334 Human

SwissProt: Q61190 Mouse

Unigene: 654593 Human

Unigene: 4154 Mouse



产品图片
Sample: Lane 1: Siha (Human) Cell Lysate at 30 ug Lane 2: U87MG (Human) Cell Lysate at 30 ug Primary: Anti-IL10RB (bs-21981R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 33 kD
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