| 产品编号 |
bsk11086 |
| 英文名称 |
Human Human CXCL1/GRO ELISA Kit |
| 中文名称 |
人趋化因子CXCL1酶联免疫试剂盒 |
| 别 名 |
CXCL1; FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1; C-X-C motif chemokine ligand 1 |
| 克 隆 号 |
|
| 种 属 |
Human |
| 线性范围 |
31.25 - 2,000 pg/mL |
| 应用范围 |
S/P/CC |
| 检测限 |
15 pg/mL |
| 适用样品基质 |
cell culture supernates, serum, and plasma. |
| 保存条件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene.CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis.CXCL1 is expressed by macrophages, neutrophils and epithelial cells,and has neutrophil chemoattractant activity.CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, arteriogenesis, inflammation, wound healing, and tumorigenesis.This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.An initial study in mice showed evidence that CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function.
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