| 产品编号 | bsm-51637M |
| 英文名称 | Natriuretic Peptide Receptor C Mouse mAb |
| 中文名称 | 利钠肽受体C单克隆抗体 |
| 别 名 | ANP C; ANPC; ANPRC; Atrial natriuretic peptide C type receptor; Atrionatriuretic peptide receptor C; Natriuretic peptide receptor C/guanylate cyclase C; NPR 3; NPR C; NPR3; NPRC; ANPRC_HUMAN. |
| 研究领域 | 心血管 信号转导 细胞膜蛋白 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | L07F1 |
| 交叉反应 | Human, |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 57 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Natriuretic Peptide Receptor C: 201-400/541 |
| 亚 型 | IgG1, k |
| 纯化方法 | affinity purified by Protein G |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. Function: Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. Subunit: Homodimer; disulfide-linked. Dimers can also be formed through the C-terminal cysteine of isoform 2. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the ANF receptor family. SWISS: P17342 Gene ID: 4883 Database links: Entrez Gene: 4883 Human SwissProt: P17342 Human |
| 产品图片 |
Sample:
Lane 1: Hela cell lysates
Primary: Anti-Natriuretic Peptide Receptor C (bsm-51637M) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 57 kD
Observed band size: 62 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
