| 产品编号 | bsm-51726M |
| 英文名称 | FAT4 Mouse mAb |
| 中文名称 | FAT4单克隆抗体 |
| 别 名 | CDHF14; FAT4_HUMAN; Cadherin family member 14; FAT tumor suppressor homolog 4; Fat-like cadherin protein FAT-J; FATJ; hFat4; Nbla00548; Protocadherin Fat 4. |
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Specific References (1) | bsm-51726M has been referenced in 1 publications.
111
[IF=3.738] Yang, Yuying. et al. FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells. MED ONCOL. 2023 Jan;40(1):1-12 WB ; Human. 222
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| 研究领域 | 肿瘤 信号转导 细胞粘附分子 细胞分化 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | H10M4 |
| 交叉反应 | Human, |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 538 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Recombinant human FAT4 between 4500-4786 amino acids |
| 亚 型 | IgG1,k |
| 纯化方法 | affinity purified by Protein G |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014] Function: May function in the regulation of planar cell polarity. Cadherins are cell-cell interaction molecules. Subcellular Location: Membrane. In the kidney, localizes to primary cilia. Tissue Specificity: Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer. Similarity: Contains 34 cadherin domains. Contains 6 EGF-like domains. Contains 2 laminin G-like domains. SWISS: Q6V0I7 Gene ID: 79633 Database links: Entrez Gene: 79633 Human SwissProt: Q6V0I7 Human Unigene: 563205 Human |
| 产品图片 |
Sample:
Lane 1: FAT4 Recombinant protein
Primary: Anti-FAT4 (bsm-51726M) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 538 kD
Observed band size: 45 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
