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Mouse Anti-Human IgM  antibody (bsm-41524M)
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说明书: 1mg  10mg  
1mg/1280.00元
10mg/6400.00元
大包装/询价

产品编号 bsm-41524M
英文名称 Mouse Anti-Human IgM
中文名称 小鼠抗人IgM单克隆抗体
别    名 human Immunoglobulin M.   鼠抗人-IgM;
抗体来源 Mouse
克隆类型 Monoclonal
交叉反应 Human, 
产品应用 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    状 Liquid
免 疫 原 Human IgM 
亚    型 IgG2a
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M PBS (pH7.4).
保存条件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

产品图片
The binding ability of antigen to antibody was detected by direct ELISA. The enzyme-labeled antibody (Anti-Human IgM Antibody-HRP (Cat. bs-41524M) specifically binds to HIgM, and has no cross reaction or weak reaction with HIgG1, HIgG4, HIgA and IgG.
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