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RatAnti-mouse CD45RB/PE antibody (bsm-30160A-PE)
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说明书: 25T  50T  100T
25T/590.00元
50T/880.00元
100T/1280.00元
大包装/询价
产品编号 bsm-30160A-PE
英文名称 mouse CD45RB/PE
中文名称 PE标记小鼠CD45RB单克隆抗体
抗体来源 Rat
克隆类型 Monoclonal
克 隆 号 8C7
交叉反应 (predicted: Mouse, )
产品应用 Flow-Cyt=10ul/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
检测分子量 200
性    状 Liquid
亚    型 Rat IgG2a, κ
纯化方法 Affinity purified by Protein G
缓 冲 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存条件 Store at 2-8℃. Protect from light. Avoid freezing.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naïve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.

SWISS:
P06800

Gene ID:
19264

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