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MouseAnti-human CD42b/PE antibody (bsm-30184M-PE)
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产品编号 bsm-30184M-PE
英文名称 human CD42b/PE
中文名称 PE标记人CD42b单克隆抗体
别    名 Antigen CD42b alpha; BSS; CD 42b; CD42b alpha; CD42b antigen; GLYCOCALICIN; Glycoprotein Ib (platelet) alpha polypeptide; Glycoprotein Ibalpha; GP Ib alpha; GP1B; GP1BA; GPIb alpha; MGC34595; Platelet glycoprotein Ib alpha chain; Platelet glycoprotein Ib alpha polypeptide; Platelet membrane glycoprotein 1b alpha subunit; GP1BA_HUMAN.  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 4B5
交叉反应 (predicted: Human, )
产品应用 Flow-Cyt=10ul/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 67kDa
检测分子量 145
性    状 Liquid
亚    型 Mouse IgG1, k
纯化方法 Affinity purified by Protein G
缓 冲 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存条件 Store at 2-8℃. Protect from light. Avoid freezing.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013]

SWISS:
P07359

Gene ID:
2811

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