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RabbitAnti-TGN46 Recombinant Rabbit mAb  antibody (bsm-54769R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  
50ul/1400.00元
100ul/2500.00元
大包装/询价

产品编号 bsm-54769R
英文名称 TGN46 Recombinant Rabbit mAb
中文名称 高尔基体网络整合膜蛋白重组兔单抗
别    名 TGN 46; TGN 51; TGN38; TGN38 homolog; TGN38B; TGN46; TGN48; TGN51; TGOLN2; TGON2_HUMAN; Trans Golgi network integral membrane protein 2; Trans golgi network protein 2; Trans Golgi network protein TGN51; Trans-Golgi network integral membrane protein 1; Trans-Golgi network integral membrane protein 2; Trans-Golgi network protein TGN51; TTGN2.  
抗体来源 Rabbit
克隆类型
克 隆 号 18D19
交叉反应 Human,  (predicted: Mouse, )
产品应用 WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 kDa
检测分子量
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TGN46 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Function:
May be involved in regulating membrane traffic to and from trans-Golgi network.

Subcellular Location:
Cell membrane. Golgi apparatus > trans-Golgi network membrane. Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.

Tissue Specificity:
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.

SWISS:
O43493

Gene ID:
10618

Database links:

Entrez Gene: 10618 Human

Entrez Gene: 192152 Rat

Omim: 603062 Human

SwissProt: O43493 Human

Unigene: 593382 Human

Unigene: 11349 Rat



产品图片
Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human MDA-MB-231 cell lysates Lane 3: Human HeLa cell lysates Lane 4: Human HepG2 cell lysates Lane 5: Human U251 cell lysates Lane 6: Human A549 cell lysates Primary: Anti-TGN46 (bsm-54769R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: kDa Observed band size: 95 kDa
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