| 产品编号 | bsm-60774R |
| 英文名称 | Mannan Binding Lectin Recombinant Rabbit mAb |
| 中文名称 | 甘露聚糖结合凝集素重组兔单克隆抗体 |
| 别 名 | Mbl2; L-MBP; MBL; MBL-C; MBP-C; COLEC 1; COLEC1; HSMBPC; Mannan binding protein; Mannose binding lectin(protein C) 2 soluble; Mannose binding lectin 2 soluble; Mannose binding lectin; Mannose binding lectin protein C2 soluble opsonic defect; Mannose binding protein; Mannose binding protein C; Mannose binding protein C precursor; MBL 2; MBP 1; MBP; MBP C; MBP1; MBPC; MGC116832; MGC116833; Opsonic defect; protein C; Soluble mannose binding lectin; MBL2_HUMAN. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 18B9 |
| 交叉反应 | (predicted: Human, Mouse, ) |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 26 kDa |
| 检测分子量 | |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Mannan Binding Lectin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | PBS, Glycerol, BSA. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]. Function: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Subunit: Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity. Subcellular Location: Secreted. Tissue Specificity: Plasma protein produced mainly in the liver. Similarity: Contains 1 C-type lectin domain. Contains 1 collagen-like domain. SWISS: P11226 Gene ID: 4153 Database links: Entrez Gene: 4153 Human Entrez Gene: 17195 Mouse Omim: 154545 Human SwissProt: P11226 Human SwissProt: P41317 Mouse Unigene: 499674 Human Unigene: 30045 Mouse MBL （mannan binding lectin）甘露聚糖结合凝集素，MBL是一种兼有调理素和直接激活补体功能的免疫分子，参与构成抗感染的第一道防线。MBL2在发生急性期反应时由肝脏分泌，并参与天然免疫防御。凝集素配体可以存在于各种各样的微生物中，两者结合后可以导致调理作用并激活补体系统。 |
| 产品图片 |
Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Mouse Plasma tissue lysates
Primary: Anti-Mannan Binding Lectin (bsm-60774R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kDa
Observed band size: 26 kDa
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
