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RabbitAnti-EWSR1 Recombinant Rabbit mAb  antibody (bsm-54677R)
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说明书: 50ul  100ul  
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-54677R
英文名称 EWSR1 Recombinant Rabbit mAb
中文名称 尤文氏肉瘤相关EWS蛋白重组兔单克隆抗体
别    名 bK984G1.4; bK984G1.4 Ewing sarcoma breakpoint region 1 protein; Ewing sarcoma breakpoint region 1; Ewing sarcoma breakpoint region 1 protein; Ewings sarcoma EWS Fli1 type 1 oncogene; EWS; EWS oncogene; EWS_HUMAN; EWSR 1; Ewsr1; EWSR1 protein; RNA binding protein EWS; RNA-binding protein EWS.  
抗体来源 Rabbit
克隆类型
克 隆 号
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 68 kDa
检测分子量
性    状 Liquid
浓    度 1mg/ml
免 疫 原 Recombinant Human EWSR1 protein 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 EWS is a nuclear RNA-binding protein. As a result of chromosome translocation, the EWS gene is fused to a variety of transcription factors, including ATF-1 in human neoplasias. In the Ewing family of tumors, the N-terminal domain of EWS is fused to the DNA-binding domain of various ETS transcription factors, including Fli-1, Erg, ETV1, E1AF and FEV. The EWS/Fli-1 chimeric protein acts as a more potent transcriptional activator than Fli-1 and can promote cell transformation. Two functional regions have been identified in EWS; an amino-terminal region (domain A), that has little transactivation activity but transforms efficiently when fused to Fli-1, and a distal region (domain B), which shows transactivation activity but transforms less efficiently when fused to Fli-1.

SWISS:
Q01844

Gene ID:
2130

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