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RabbitAnti-Reelin Recombinant Rabbit mAb  antibody (bsm-54065R)
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说明书: 50ul  100ul  
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-54065R
英文名称 Reelin Recombinant Rabbit mAb
中文名称 络丝蛋白重组兔单抗
别    名 Reeler; RELN; RL; LIS2; PRO1598; RELN_HUMAN.  
抗体来源 Rabbit
克隆类型
克 隆 号
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 388 kDa
检测分子量
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 A synthesized peptide derived from human Reelin: 3240-3300/3460 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in “reeler” mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1 in a signaling pathway that controls cell positioning in the developing brain and is also thought to be a direct effector of the neurotrophin BDNF.

SWISS:
P78509

Gene ID:
5649

Reelin蛋白作用目前还在进一步研究中,但有学者认为它与β-Amyloid 的神经缠结有相对应的作用。
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