| 产品编号 | bsm-55521R |
| 英文名称 | Phospho-JNK (T183/Y185) Recombinant Rabbit mAb |
| 中文名称 | 磷酸化氨基末端激酶重组兔单抗 |
| 别 名 | JNK1+JNK2+JNK3; JNK1/2/3; JNK1+2+3; MAPK8; MAPK9; MAPK10; c Jun N terminal kinase 1; c Jun N terminal kinase 2; c Jun N terminal kinase 3; P-JNK0 |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | SB97 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 46/54 kDa |
| 检测分子量 | 46/54 |
| 性 状 | Liquid |
| 免 疫 原 | KLH conjugated Synthetic phosphopeptide derived from Human JNK(T183/Y185) |
| 亚 型 | IgG |
| 纯化方法 | Affinity Purification |
| 缓 冲 液 | PBS with 100 μg/ml BSA,0.15% ProClin300 and 50% glycerol. |
| 保存条件 | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. SWISS: P45983 Gene ID: 5599 丝氨酸/苏氨酸蛋白激酶参与多种过程，如细胞增殖、分化、迁移、转化和程序性细胞死亡。细胞外刺激如促炎细胞因子或物理应激刺激应激激活的蛋白激酶/c-Jun N-末端激酶（SAP/JNK）信号通路。应激激活的蛋白激酶/Jun氨基末端激酶SAPK/JNK可有效、优先被各种环境应激被激活，这些应激反应包括紫外线和γ辐射、神经酰胺和炎性细胞因子，以及生长因子和GPCR激动剂（在某些情况下）。与其它MAPK一样，核心信号转导单元由一个MAPKKK（一般为MEKK1-MEKK4），或一个能磷酸化和激活MKK4/7的混合谱 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
