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MouseAnti-Human CG beta Mouse mAb  antibody (bsm-43172M)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bsm-43172M
英文名称 Human CG beta Mouse mAb
中文名称 人绒毛膜促性腺激素β单克隆抗体
别    名 CGB5; CGB8; CGB3_HUMAN;Choriogonadotropin subunit beta (CG-beta); Chorionic gonadotropin chain beta, Choriogonadotropin subunit beta 3  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 3F4
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 18 kDa
检测分子量
细胞定位 分泌型蛋白 
性    状 Liquid
免 疫 原 Recombinant human Choriogonadotropin subunit beta 3 protein 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Function:
Encoded by a cluster of genes that have evolved by duplication from LHB. HCG-beta is encoded by six non-allelic genes (CGB) clustered on chromosome 19q13.3 and named CGB1, CGB2, CGB3, CGB5, CGB7 and CGB8. Two specific hCGb proteins that differ by three amino acids in positions 2,4 and 117 have been described: type 1 (CGB7) and type 2 (CGB3, CGB5, CGB8). The CGB gene first arose in the common ancestor of the anthropoid primates.

Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in placenta, testis and pituitary.

Similarity:
Belongs to the glycoprotein hormones subunit alpha family.

SWISS:
P0DN86

Gene ID:
1082

Database links:

Entrez Gene : 1082 Human

SwissProt : P0DN86 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded Human placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Human CG beta Monoclonal Antibody, Unconjugated(bsm-43172M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
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