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MouseAnti-SERPINB3 Mouse mAb  antibody (bsm-43190M)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bsm-43190M
英文名称 SERPINB3 Mouse mAb
中文名称 丝氨酸蛋白酶抑制剂B3单克隆抗体
别    名 HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 3; Serpin B3; Serpin peptidase inhibitor clade B (ovalbumin) member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A.  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 46 kDa
检测分子量
细胞定位 细胞浆 分泌型蛋白 
性    状 Liquid
免 疫 原 Recombinant human SERPINB3 protein 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍

Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]




Function:
May act as a protease inhibitor to modulate the host immune response against tumor cells.

Subcellular Location:
Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.

Tissue Specificity:
Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

SWISS:
P29508

Gene ID:
6317

Database links:

Entrez Gene : 6317 Human

Omim : 600517 Human

SwissProt : P29508 Human

Unigene : 227948 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded Human Esophagus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Prostate; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Cervical Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Lung squamous cell carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
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