| 产品编号 | bsm-63282R |
| 英文名称 | phospho-Tau (S356) Recombinant Rabbit mAb |
| 中文名称 | 磷酸化微管相关蛋白重组兔单抗 |
| 别 名 | DDPAC; MAPT; MAPTL; MSTD; Mtapt; MTBT1; MTBT2; PHF tau; PPND; pTau; RNPTAU; TAU. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 4C2 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 79 kDa |
| 检测分子量 | 50-70 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Tau around the phosphorylation site of S356: SKIG-pS-LDN |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. SWISS: P10636 Gene ID: 4137 tau蛋白是脑内神经元细胞支架蛋白之一.其正常功能是促进微管蛋白组成微管,并维持已形成微管的稳定性.参与维持细胞形态、信息传递、细胞分裂等重要生物学过程,是轴突生长发育和神经元极性形成的不可缺少因素. 近年来发现tau蛋白与一些中枢神经系统变性疾病密切相关,尤其是神经Tau具有启动微管系统的装配以及稳定微管系统的作用，该蛋白的错误折叠与老年性痴呆等神经退行性疾病密切相关. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
