| 产品编号 | bsm-63283R |
| 英文名称 | phospho-CHEK1 (S280) Recombinant Rabbit mAb |
| 中文名称 | 磷酸化细胞周期检测点激酶1重组兔单抗 |
| 别 名 | Checkpoint kinase 1; Chek1; Chk1; rad27. |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 5D11 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 54 kDa |
| 检测分子量 | 54 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Chk1 around the phosphorylation site of S280: VT-pS-GG |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. SWISS: O14757 Gene ID: 1111 Chk1作为Cdks的调节参与细胞周期调节过程,是生物进化过程中非常保守的蛋白激酶，在DNA损伤引起的细胞周期检测点调节中有着非常重要的作用.在细胞周期检测点信号传导通路中，Chkl和Chk2起着重要作用，主要参与G2/M期细胞周期检测点信号传导. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
