| 产品编号 | bsm-63298R |
| 英文名称 | phospho-Beta Catenin (T41/S45) Recombinant Rabbit mAb |
| 中文名称 | 磷酸化β 连环素蛋白重组兔单抗 |
| 别 名 | CTNB1_HUMAN; Catenin beta-1; catenin beta 1; CTNNB1; Catenin beta; Beta-catenin; CTNNB; OK/SW-cl.35; PRO2286; EVR7; MRD19; NEDSDV; armadillo; βcatenin; β catenin; β-catenin; |
| 抗体来源 | Rabbit |
| 克隆类型 | |
| 克 隆 号 | 1B5 |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 85 kDa |
| 检测分子量 | 92 |
| 性 状 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human beta Catenin around the phosphorylation site of T41/S45: SGAT-pT-TAP-pS-LSGK |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. SWISS: P35222 Gene ID: 1499 细胞粘附蛋白（Call Adhesion Protein） β连环素蛋白β-catenin是一种多功能的蛋白质，能链接E-\N-,钙粘附分子具有参与细胞粘附和介导信号转导的双重功能，并与肿瘤的发生发展及浸润密切相关。 在正常个体中，β-catenin和钙黏蛋白形成复合体，介导同型细胞的粘附，维持细胞的稳定；同时，β-catenin作为Wnt/β-catenin信号通路的关键成员在介导信号转导过程中调控细胞的增殖和凋亡。 在恶性肿瘤中，β-catenin的表达呈现明显的异质性，促使细胞异常增殖，还可使细胞之 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
