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Mouse BDNF Ready-To-Use IHC Kit (IHC0324M)
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说明书: 50T  
50T/3200.00元
大包装/询价

产品编号 IHC0324M
英文名称 Mouse BDNF Ready-To-Use IHC Kit
中文名称 小鼠脑源神经营养因子即用型免疫组化试剂盒
别    名 ANON2, BULN2, Abrineurin, BDNF, BDNF_HUMAN, Brain Derived Neurotrophic Factor, Brain-derived neurotrophic factor, MGC34632, MGC34632, Neurotrophin  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Although further processing generates the mature, 14 kDa protein, pro-BDNF is biologically active and is secreted in synaptic vesicles along with the mature form. BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons. Signaling occurs mainly through the tyrosine kinase receptor TrkB, although binding to the lower-affinity receptor, p75-NTR, has also been demonstrated. BDNF promotes neuronal survival and differentiation and has been shown to play a critical role in memory formation and synaptic regulation. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients, and may also play a role in the regulation of stress response and in the biology of mood disorders.

SWISS:
P23560

Gene ID:
627

产品图片
Immunohistochemical analysis of paraffin embedded mouse brain tissue slide using IHC0324M (Mouse BDNF Kit).
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