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Human SCF Ready-To-Use IHC Kit (IHC0338H)
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说明书: 50T  
50T/3200.00元
大包装/询价

产品编号 IHC0338H
英文名称 Human SCF Ready-To-Use IHC Kit
中文名称 人干细胞生长因子即用型免疫组化试剂盒
别    名 DCUA, DFNA69, FPH2, FPHH, KL-1, SCF, Stem Cell Factor, C kit ligand, Ckit ligand, DKFZp686F2250, KIT ligand, Kitl, KITLG, KL 1, KL1, Mast cell growth factor, MGF, SF, SHEP7, Steel factor, Stem cell factor precursor, SCF_HUMAN  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.

SWISS:
P21583

Gene ID:
4254

产品图片
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0338H (Human SCF Kit).
Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0338H (Human SCF Kit).
Immunohistochemical analysis of paraffin embedded human prostate tumor tissue slide using IHC0338H (Human SCF Kit).
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