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Human WT1 Ready-To-Use IHC Kit (IHC0358H)
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说明书: 50T  
50T/3200.00元
大包装/询价

产品编号 IHC0358H
英文名称 Human WT1 Ready-To-Use IHC Kit
中文名称 人肾母细胞瘤蛋白即用型免疫组化试剂盒
别    名 AWT1, D630046I19Rik, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, Wt-1, WT1, WT33, Wilms tumor 1  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 The Wilms Tumor 1 gene encodes one of the WPP domain-interacting proteins (Wilms Tumor 1/AT5G11390, WIT2/AT1G68910) required for RanGAP nuclear envelope association in root tip cells. Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly. The cytoplasmic Ran GTPase activating protein RanGAP is critical to establish a functional RanGTP/RanGDP gradient across the nuclear envelope and is associated with the outer surface of the nuclear envelope in metazoan and higher plant cells. Arabidopsis thaliana RanGAP association with the root tip nuclear envelope requires a family of likely plant-specific nucleoporins combining coiled-coil and transmembrane domains (CC-TMD) and WPP domain-interacting proteins (WIPs). Wilms Tumor 1 and WIT2 have been identified as a second family of CC-TMD proteins, structurally similar, yet clearly distinct from the WIP family, that is required for RanGAP nuclear envelop association in root tip cells.

SWISS:
P19544

Gene ID:
7490

产品图片
Immunohistochemical analysis of paraffin embedded human testis tissue slide using IHC0358H (Human WT1 Kit).
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