产品编号 | IHC0363H |
英文名称 | Human CD3E Ready-To-Use IHC Kit |
中文名称 | 人CD3E即用型免疫组化试剂盒 |
别 名 | 4930549J05Rik, A430104F18Rik, AI504783, AW552088, CD247, CD3, CD3-DELTA, Cd3-eta, CD3-GAMMA, CD3-ZETA, CD3D, CD3E, CD3epsilon, CD3G, CD3H, CD3Q, CD3Z, Cd3zeta, Ctg-3, Ctg3, IMD17, IMD18, IMD19, IMD25, T3D, T3E, T3G, T3Z, TCRE, Tcrk, TCRZ, CD3 epsilon, CD3 |
适用样品基质 | FFPE tissue |
保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
产品介绍 |
The CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. The genes encoding the CD3 epsilon, gamma and delta polypeptides are located on chromosome 11. Defects in the CD3 gene are associated with CD3 immunodeficiency. SWISS: P07766 Gene ID: 916 |
产品图片 |
Immunohistochemical analysis of paraffin embedded human thymus tissue slide using IHC0363H (Human CD3E Kit).
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0363H (Human CD3E Kit).
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |