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RabbitAnti-LASS3 Rabbit pAb  antibody (bs-24625R)
~~~促销,代码KXJ230206~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-24625R
英文名称 LASS3 Rabbit pAb
中文名称 长寿相关基因lASS3抗体
别    名 LAG1 longevity assurance homolog 3; CerS3; LAG1 homolog, ceramide synthase 3; LASS 3; MGC 27091; CERS3_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse, Rat, 
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 46 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse LASS3: 301-3893/383 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 LASS3 is a 383 amino acid membrane protein almost exclusively expressed in testis, suggesting that LASS3 plays an important role in proper testis function. It is also weakly expressed in skin. A transcriptional variant of LASS3 cDNA exists and can result in the production of a 419 amino acid protein (LASS3-long). LASS3 overproduction raises the level of several ceramide species, including C18:0- and C24:0-ceramides.

Function:
May be involved in sphingolipid synthesis or its regulation

Subcellular Location:
Nucleus membrane; Multi-pass membrane protein

Similarity:
Contains 1 homeobox DNA-binding domain.
Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Gene ID:
545975

Database links:

Entrez Gene: 204219 Human

Entrez Gene: 545975 Mouse

Entrez Gene: 499174 Rat

SwissProt: Q8IU89 Human

Unigene: 662371 Human



产品图片
Sample: Lane 1: Testis (Mouse) Tissue Lysate at 40 ug Lane 2: Testis (Rat) Tissue Lysate at 40 ug Lane 3: Ear (Rat) Tissue Lysate at 40 ug Lane 4: Esophagus (Rat) Tissue Lysate at 40 ug Primary: Anti-LASS3 (bs-24625R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kD Observed band size: 46 kD
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