| 产品编号 | bs-101791P |
| 英文名称 | Recombinant Human PPARD Protein, N-His |
| 中文名称 | |
| 别 名 | PPARD; Nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; NR1C2; NUC1; Peroxisome proliferator-activated receptor delta; PPAR-beta; PPAR-delta; PPARB; NUCI; Peroxisome proliferator-activated receptor beta |
| 克 隆 号 | |
| 理论分子量 | 21.19 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Heterodimer with the retinoid X receptor. Subcellular located at nuclear Tissue specificity: Heart, adrenal and intestine. Belongs to the nuclear hormone receptor family. NR1 subfamily. It Contains 1 nuclear receptor DNA-binding domain. SWISS: Q03181 Gene ID: 5467 类固醇受体(Steroid Receptors) 研究人员指出该分子的功能,极可能就是阻断心血管免疫发炎反应的讯号传递过程。PPAR-delta基因是控制肌肉发展的重要基因,在增加老鼠耐力的同时还能帮助它燃烧掉脂肪,研究人员发现,对于与新陈代谢有关的各项疾病,从心脏病到肥胖症都有启发性的意义,他可以阻止脂肪沉淀在动脉壁上,进而防止动脉硬化症的发生,该蛋白参与脂肪代谢、肥胖、糖尿病、动脉硬化和癌症的发病。 在动脉硬化现象发生的早期,免疫细胞会促使血管慢性的发炎,因而造成血管不断地吸收和输送脂肪,进而导致脂肪 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |