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产品中心-北京博奥森生物技术有限公司
Recombinant Human PPARD Protein, N-His (bs-101791P)
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说明书: 20ug  50ug  100ug
20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-101791P
英文名称 Recombinant Human PPARD Protein, N-His
中文名称
别    名 PPARD; Nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; NR1C2; NUC1; Peroxisome proliferator-activated receptor delta; PPAR-beta; PPAR-delta; PPARB; NUCI; Peroxisome proliferator-activated receptor beta  
克 隆 号
理论分子量 21.19 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Heterodimer with the retinoid X receptor. Subcellular located at nuclear Tissue specificity: Heart, adrenal and intestine. Belongs to the nuclear hormone receptor family. NR1 subfamily. It Contains 1 nuclear receptor DNA-binding domain.

SWISS:
Q03181

Gene ID:
5467

类固醇受体(Steroid Receptors) 研究人员指出该分子的功能,极可能就是阻断心血管免疫发炎反应的讯号传递过程。PPAR-delta基因是控制肌肉发展的重要基因,在增加老鼠耐力的同时还能帮助它燃烧掉脂肪,研究人员发现,对于与新陈代谢有关的各项疾病,从心脏病到肥胖症都有启发性的意义,他可以阻止脂肪沉淀在动脉壁上,进而防止动脉硬化症的发生,该蛋白参与脂肪代谢、肥胖、糖尿病、动脉硬化和癌症的发病。 在动脉硬化现象发生的早期,免疫细胞会促使血管慢性的发炎,因而造成血管不断地吸收和输送脂肪,进而导致脂肪
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