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Recombinant Human TNK2 Protein, N-His (bs-101836P)
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说明书: 20ug  50ug  100ug
20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-101836P
英文名称 Recombinant Human TNK2 Protein, N-His
中文名称
别    名 ACK-1; ACK1; TNK2; Activated CDC42 kinase 1; Tyrosine kinase non-receptor protein 2  
克 隆 号
理论分子量 32.08 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq].

SWISS:
Q07912

Gene ID:
10188

Ack 1分子是一组促进酪氨酸激酶生长的家族成员,该蛋白与肿瘤分裂、生长、转移起到很重要的作用,可加速恶性肿瘤的浸润。
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