| 产品编号 | bs-101885P |
| 英文名称 | Recombinant Human STK4 Protein, N-His |
| 中文名称 | |
| 别 名 | KRS2; STK4; MST1/N; MST1/C; MST1; MST-1; Serine/threonine-protein kinase 4; Mammalian STE20-like protein kinase 1; STE20-like kinase MST1; Serine/threonine-protein kinase Krs-2 |
| 克 隆 号 | |
| 理论分子量 | 20.4 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008] SWISS: Q13043 Gene ID: 6789 蛋白激酶MST(Mammalian Sterile20-like Kinase) 是各种组织均有表达的丝氨酸/苏氨酸（Serine/Threonine）蛋白激酶。属于人丝氨酸/苏氨酸激酶的哺乳动物STE20样激酶(MST)，MST1和MST2在caspase蛋白酶激活的细胞凋亡的上游和下游都起作用。 细胞凋亡中MST1被caspase蛋白酶切割和激活，能诱导细胞凋亡形态上的改变如染色质凝聚。哺乳动物STE20样激酶2 (Mst2) 与Mst1蛋白激酶很相似,有近90%的同源性。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
