| 产品编号 | bs-101890P |
| 英文名称 | Recombinant Human TRAF3 Protein, N-His |
| 中文名称 | |
| 别 名 | CAP-1; RING-type E3 ubiquitin transferase TRAF3; LAP1; LMP1-associated protein 1; TRAF3; CD40-binding protein; TNF receptor-associated factor 3; CD40BP; CAP1; CRAF1; CD40 receptor-associated factor 1 |
| 克 隆 号 | |
| 理论分子量 | 41.78 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]. SWISS: Q13114 Gene ID: 7187 TRAF3是作用最为广泛的一种TRAF蛋白，它可以与LTb R、CD40、TNFRII和LMP1结合，并介导CD30、LMP1活化NF-kB。TRAF3与CD40结合后可以挽救凋亡的B细胞， TRAF3还参与CD40在B细胞中上调CD23的作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
