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产品中心-北京博奥森生物技术有限公司
Recombinant Human MAPK6 Protein, N-His (bs-102093P)
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说明书: 20ug  50ug  100ug
20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-102093P
英文名称 Recombinant Human MAPK6 Protein, N-His
中文名称
别    名 p97-MAPK; ERK3; PRKM6; Mitogen-activated protein kinase 6; MAP kinase isoform p97; MAPK 6; ERK-3; MAP kinase 6; Extracellular signal-regulated kinase 3; MAPK6  
克 隆 号
理论分子量 38.13 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in 50mM Tris, 150mM NaCl, pH 8.0, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein. Function : Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.

SWISS:
Q16659

Gene ID:
5597

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