| 产品编号 | bs-102149P |
| 英文名称 | Recombinant Human SIGIRR Protein, N-His |
| 中文名称 | |
| 别 名 | TIR8; Toll/interleukin-1 receptor 8; Single Ig IL-1R-related molecule; Single Ig IL-1-related receptor; Single immunoglobulin domain-containing IL1R-related protein; SIGIRR |
| 克 隆 号 | |
| 理论分子量 | 14.85 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Single Ig IL-1-related receptor SIGIRR, also designated single immunoglobulin domain-containing IL-1R-related protein or Toll/interleukin-1 receptor 8 (TIR8), is a member of the interleukin-1 receptor family. SIGIRR acts as a negative regulator of the IL-1R and Toll-like receptor signaling pathways and reduces the recruitment of certain components to the TLR4 receptor. Subsequently, SIGIRR confers resistance to P. aeruginosa corneal infection. SIGIRR can form complexes with IL-1R1, MYD-88, IRAK-1 and TRAF-6 upon IL-1 stimulation and TLR4 after LPS stimulation. It is a single-pass type III membrane protein that is mainly expressed in kidney, lung and gut. SWISS: Q6IA17 Gene ID: 59307 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
