| 产品编号 | bs-102248P |
| 英文名称 | Recombinant Human SFRP1 Protein, N-His |
| 中文名称 | |
| 别 名 | Secreted apoptosis-related protein 2; FRP-1; SARP2; SARP-2; sFRP-1; FRP; SFRP1; FRP1; Secreted frizzled-related protein 1 |
| 克 隆 号 | |
| 理论分子量 | 34.85 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009] SWISS: Q8N474 Gene ID: 6422 分泌型卷曲相关蛋白1是近来发现的新的抑癌基因, 是Wnt信号通道的拮抗通路蛋白,SFRP1能够阻断某些发生在癌症初期与之相关的细胞生长基因的信号通路。 有学者认为：该基因有去甲基化酶的作用，可以阻断与甲基化进程相关酶的活性，进而抑制肿瘤基因的改变，SFRP1的作用还有待于更进一步的研究。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
