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Human EGFR Ready-To-Use IHC Kit (IHC0406H)
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说明书: 50T  
50T/3200.00元
大包装/询价

产品编号 IHC0406H
英文名称 Human EGFR Ready-To-Use IHC Kit
中文名称 人表皮生长因子受体即用型免疫组化试剂盒
别    名 9030024J15Rik; AI552599; ERBB; ERBB1; Errp; NISBD2; wa-2; EGFR; Avian erythroblastic leukemia viral (v erb b) oncogene homolog; Avian erythroblastic leukemia viral (verbb) oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing pr  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 EGFR, epidermal growth factor receptor, is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. EGFR is encoded by the EGFR gene located on chromosome 7 in humans. EGFR belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4. EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor alpha) to the extracellular domain leads to EGFR dimerization followed by autophosphorylation of the tyrosine residues in the cytoplasmic domain. Overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.

SWISS:
P00533

Gene ID:
1956

产品图片
Immunohistochemical analysis of paraffin embedded human placenta tissue slide using IHC0406H (Human EGFR IHC Kit).
Immunohistochemical analysis of paraffin embedded human abdominal skin tissue slide using IHC0406H (Human EGFR IHC Kit).
Immunohistochemical analysis of paraffin embedded human lung squamous cell carcinoma tissue slide using IHC0406H (Human EGFR IHC Kit).
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