| 产品编号 | IHC0409R |
| 英文名称 | Rat p27 KIP 1 Ready-To-Use IHC Kit |
| 中文名称 | 大鼠P27/周期素依赖激酶抑制剂即用型免疫组化试剂盒 |
| 别 名 | AA408329; AI843786; CDKN1B; CDKN4; KIP1; MEN1B; MEN4; p27; P27KIP1; p27 KIP 1; CDN1B_HUMAN; Cdki1b; CDKN 1B; CDKN 4; Cyclin Dependent Kinase Inhibitor 1B; Cyclin Dependent Kinase Inhibitor 1B |
| 适用样品基质 | FFPE tissue |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 产品介绍 |
p27 Kip1 functions as a negative regulator of G1 mouse expression and has been proposed to function as a possible mediator of TGFb induced G1 arrest. p27 Kip1 is an important regulator of cell cycle progression, a potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. p27 Kip1 forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. p27 Kip1 acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. p27 Kip1 has a molecular weight of approximately 27kDa and the degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. SWISS: P46414 Gene ID: 12576 |
| 产品图片 |
Immunohistochemical analysis of paraffin embedded rat brain tissue slide using IHC0409R (Rat p27 KIP 1 IHC Kit).
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
