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Human TARDBP Ready-To-Use IHC Kit (IHC0429H)
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说明书: 50T  
50T/3200.00元
大包装/询价

产品编号 IHC0429H
英文名称 Human TARDBP Ready-To-Use IHC Kit
中文名称 人Tar DNA 结合蛋白43即用型免疫组化试剂盒
别    名 1190002A23Rik; ALS10; C85084; TARDBP; TDP-43; TDP43; wu:fb77f02; wu:fc52g10  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.

SWISS:
Q13148

Gene ID:
23435

产品图片
Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0429H (Human TARDBP IHC Kit).
Immunohistochemical analysis of paraffin embedded human glioma tissue slide using IHC0429H (Human TARDBP IHC Kit).
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