产品编号 | IHC0469H |
英文名称 | Human TNFAIP3 Ready-To-Use IHC Kit |
中文名称 | 人肿瘤坏死因子α诱导蛋白3即用型免疫组化试剂盒 |
别 名 | Tnfip3; A20; AISBL; OTUD7C; TNFA1P2; AISBL; MGC104522; MGC138687; MGC138688; OTU domain containing protein 7C; OTU domain-containing protein 7C; OTUD7C; Putative DNA binding protein A20; Putative DNA-binding protein A20; TNAP3_HUMAN; TNF alpha-induced pro |
适用样品基质 | FFPE tissue |
保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
产品介绍 |
TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-a, inhibiting NF-kappa-B-dependent gene expression, and protecting cells from TNF-a-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist. SWISS: P21580 Gene ID: 7128 |
产品图片 |
Immunohistochemical analysis of paraffin embedded human placenta tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
|
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |