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Human TNFAIP3 Ready-To-Use IHC Kit (IHC0469H)
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说明书: 50T  
50T/3200.00元
大包装/询价

产品编号 IHC0469H
英文名称 Human TNFAIP3 Ready-To-Use IHC Kit
中文名称 人肿瘤坏死因子α诱导蛋白3即用型免疫组化试剂盒
别    名 Tnfip3; A20; AISBL; OTUD7C; TNFA1P2; AISBL; MGC104522; MGC138687; MGC138688; OTU domain containing protein 7C; OTU domain-containing protein 7C; OTUD7C; Putative DNA binding protein A20; Putative DNA-binding protein A20; TNAP3_HUMAN; TNF alpha-induced pro  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-a, inhibiting NF-kappa-B-dependent gene expression, and protecting cells from TNF-a-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist.

SWISS:
P21580

Gene ID:
7128

产品图片
Immunohistochemical analysis of paraffin embedded human placenta tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
Immunohistochemical analysis of paraffin embedded human hepatocellular carcinoma tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
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